Potential of Theranostics in Visualisation of the Tumour Microenvironment and Elimination of Its Immunosuppressive Components

Theranostics is a promising branch of nuclear medicine that uses radiopharmaceuticals for diagnosis and treatment cancer, immunotheranostics special area in it. The aim the study was to summarise potential theranostics visualisation tumour microenvironment elimination its immunosuppressive components. article presents up-to-date information on composition interaction various cell subpopulations microenvironment, as well role cancer stem cells formation. It describes defects signalling pathways targets cells. Also, provides description mechanism between immune system process carcinogenesis. review offers detailed analysis approaches assessing type order individualise develop rational design clinical studies theranostic couples. authors present their own data distribution lymphocytes myeloid-derived suppressor patients with metastatic tumours. have considered nuances creating using molecules targeted delivery development diagnostic therapeutic radiopharmaceuticals. most isotopes are described from point view possibility influencing highlights modern methods pre-targeting reduce toxicity increase effectiveness theranostics. Furthermore, having compared advantages disadvantages those other systemic options tumours, outline possible ways overcome shortcomings